The music video is set in an urban environment, reflecting the roots of both rock and hip-hop music. The video opens with a scene of Run-D.M.C. crashing through a wall, symbolizing their entrance into the world of rock music. As the song progresses, viewers are taken on a journey through the gritty streets, alleys, and rooftops of the city, where both Aerosmith and Run-D.M.C. perform their respective parts of the song. The video also features dance sequences and energetic performances from both groups, highlighting their unity and collaboration. Throughout the video, there's a sense of rebellion and defiance, as the artists assert their presence and break down barriers in a music industry that was often divided along racial and genre lines. Overall, the setting and story portrayed in the video complement the song's themes of unity, empowerment, and breaking down barriers, making it a powerful visual representation of the very first time worlds collided!